This category of nonnutritive, high-intensity sugar substitutes includes aspartame, acesulfame-K and saccharin. Two sweeteners undergoing FDA approval at this writing are alitame and sucralose. Cyclamate lost its FDA approval in 1970. Numerous new sweeteners are in various stages of development or review. Most of these are from two groups: the fructo-oligosaccharides (fos) and the L-sugars.